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Re: 7 years of therapy and only 2 months NORMAL » Jeroen

Posted by Racer on July 16, 2008, at 9:56:08

In reply to Re: 7 years of therapy and only 2 months NORMAL, posted by Jeroen on July 16, 2008, at 4:53:14

> hi philippa i asked for Sulpiride and the doctor dont want to prescribe it,


Jeroen, what's going on with the clozapine? Have you reached a therapeutic dose yet? What sorts of side effects are bothering you?

I've read your posts for a long time here, and I know you're in a lot of distress. What worries me, though, as I've said before, is that if you give up on medications before reaching a therapeutic dose, you may miss out on a treatment which would satisfy your needs. Believe me -- I do know how hard it is to continue a drug trial when you're not noticing any benefits. On the other hand, sometimes we have to go through those periods in order to feel better. Although you've complained that nothing has worked for you so far, you have also stopped medication trials very rapidly, before one might expect to see beneficial results.

The standard used to describe treatment refractory disorders is failure of an adequate dose for an adequate duration. So far, the trials you've described don't seem to have reached either adequate dosage or adequate duration. Maybe if you could find a way to tolerate the start up phase, you'd find that the medications might work better than you have experienced to date? Perhaps your doctor could help support you in tolerating the start up phase?

Also, because some of these medications require blood level monitoring, and because drug interactions can be a significant issue, it might not be in your best interest to prescribe for yourself. I hope that you will at least discuss with your doctor his reasons for not prescribing sulpiride. It could be that he has some pretty compelling reasons, and that you'd do well to consider them.

I wish you the best.


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