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Re: Tianeptine + Desipramine

Posted by Quintal on July 3, 2008, at 15:14:00

In reply to Tianeptine + Desipramine, posted by satsumas on July 3, 2008, at 13:35:29

I am interested in this question too because I will probably have to switch to lofepramine (metabolizes into desipramine) when I run out of tianeptine.

>I wanted to try tianeptine but my doctor suggested desipramine first as he hadn't had much experience with tianeptine and said that a well known bipolar researcher at Stanford wasn't all that enthused about tianeptine's efficacy in BP depression.

I have bipolar I and tianeptine has worked for me. It's the only antidepressant that has worked consistently.

>Is it OK to take desipramine with tianeptine?

Yes, I think so. There isn't a great deal of information about potential interactions with tianeptine though.

>y Dr. hinted that they both are effectively doing the "same thing" with tianeptine increasing norep via its decrease of serotonin, but i'm not so sure about that.

I don't think so. It doesn't feel like a nordarenergic drug in any way to me. I suspect he just doesn't want you to take tianeptine, period.

>Does anyone have any experience with this combo?

No, but I did take it with reboxetine with awful results, but that turned out to be just the reboxetine.

Q (Formerly Horned One)




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