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Re: Rocket Fuel Failed; What Magic Combo Is Next? » Phillipa

Posted by Crotale on June 17, 2008, at 21:02:27

In reply to Re: Rocket Fuel Failed; What Magic Combo Is Next? » Bob, posted by Phillipa on June 9, 2008, at 21:20:35

> Good question really although xanax has a slight mood elevating property it needs to be taken frequently and valium lasts a long time. Phillipa

As I understand it, this isn't really correct: Valium has a long elimination half-life; however, it doesn't actually have a very long *duration of action*. The reason has to do with volume of distribution. Valium is taken up into the CNS quickly but then gets redistributed rather quickly throughout the body. It doesn't do you much good if it's sitting in your big toe.

A neuropharmacologist could explain this better. Anybody?


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