Posted by Crotale on June 17, 2008, at 20:27:33
In reply to Trazadone is perfectly safe with Emsam!!, posted by dcruik518 on June 16, 2008, at 19:45:23
Agreed; trazodone *might* not be safe with MAOIs in much higher doses, like 300 or 400mg (at which it *is* a serotonin reuptake inhibitor), but the 50mg or so usually used for insomnia is fine with MAOIs.
Personally I found that trazodone (and most other drugs that are sedating because they antagonize type-1 histamine receptors -- like Benadryl, tricyclic antidepressants, Atarax, antipsychotics like Mellaril and Zyprexa, etc.) stopped working after a few days when I tried to use it for insomnia. I kept having to increase the dose or the sleeping pills stopped working. So in the end they didn't really work out for me. But trazodone helps a lot of people who get insomnia on MAOIs (a very common side effect, as well as a common symptom of depression).
> The whole thing about trazodone being contraindicated with MAOI's is b*llsh*t. I took Parnate, Nardil, and Selegeline all with Trazadone and never had a problem--although one or two pharmacists mentioned it. The threat of serotonin syndrome is only with the SSRI's of which Trazodone is not one! It's perfectly safe and likely the only drug strong enough to overcome your insomnnia. Go to a different pharmacy!!!
poster:Crotale
thread:826808
URL: http://www.dr-bob.org/babble/20080617/msgs/835157.html