Posted by SLS on June 15, 2008, at 5:31:51
In reply to Re: does selegiline really mitigate DAergic cell loss?, posted by undopaminergic on June 14, 2008, at 17:45:49
Wow!
What an excellent treatise on selegiline!
I don't know how you have come to possess so much knowledge, but your presentation was wonderful. I have followed the development of L-deprenyl since 1983 when it was first being developed as an antidepressant.
How in the world did you know about clorgyline and the propargyl class of MAOIs? Clorgyline is the most efficacious antidepressant that presently exists. Unfortunately, the patent on it ran out long ago, and two cardiac-related deaths were reported at the NIH. While I was a research patient at the NIH, clorgyline was the physician's "ace in the whole" as they called it. At the moment, clorgyline is no longer being manufactured for human consumption. However, as a biological probe, it is the de facto marker of MAOI-A enzyme concentration.
Again, I would like to offer you praise for your post composition, as it is worded extremely well and is extremely accurate.
Thanks.
- Scott
poster:SLS
thread:834421
URL: http://www.dr-bob.org/babble/20080606/msgs/834708.html