Posted by linkadge on May 28, 2008, at 20:47:33
In reply to Re: cholinergic med counter to nardil sex. dysfunc, posted by SLS on May 28, 2008, at 12:41:58
I don't really think that the REM supression theory is a good model for all affective disorders.
It is clear that certain forms of depression are associated with enhanced REM, but I don't think that a potent REM supressor is necessarily needed to correct that.
I think one study showed that after a month or so on trimipramine, the depressed sleep profile improved to resemble a more healthy state. But, trimipramine doesn't necessarily need to be a potent, fast acting REM supressor to accomplish this.