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Re: Suboxone???? Is it only for Opiates or an Ad Too?

Posted by undopaminergic on May 28, 2008, at 18:40:00

In reply to Re: Suboxone???? Is it only for Opiates or an Ad Too? » undopaminergic, posted by okydoky on May 28, 2008, at 18:07:34

> My doctor had asked me to give him a list of narcotic analgesic that myinsurence would cover. So I have a lost. How do I go about looking up whether it is a kappa-opioid receptor antagonist?
>

You could search PubMed and the web, although sometimes the results are ambiguous and a definite answer will remain elusive.

As far as I know, most of the drugs on the market are either agonists at - or have negligible affinity to - the kappa-receptor.

The most potent kappa-antagonist is buprenorphine, followed by naltrexone and naloxone - and those three are the only ones clinically available to my knowledge.


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