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Re: Sleep meds » NewHampshireGuy

Posted by Jedi on May 26, 2008, at 2:35:03

In reply to Re: Sleep meds, posted by NewHampshireGuy on May 25, 2008, at 11:27:42

Hi,
I just use Seroquel for the histamine affect. 25mg knocks me out in about an hour. I've been taking it for over a year for this with no tolerance built up. There are some studies which suggest that adjunctive Seroquel at higher dosages can help with treatment resistant GAD.

J Anxiety Disord. 2008 Mar 13.
Quetiapine as an adjunctive pharmacotherapy for the treatment of non-remitting generalized anxiety disorder: A flexible-dose, open-label pilot trial.
Link: http://www.ncbi.nlm.nih.gov/pubmed/18455360?
ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Seroquel is also being studied as an augmentation for ADs in treatment resistant depression:

Hum Psychopharmacol. 2007 Jan;22(1):1-9.
Effects of adjunctive antidepressant therapy with quetiapine on clinical outcome, quality of sleep and daytime motor activity in patients with treatment-resistant depression.
Link: http://www.ncbi.nlm.nih.gov/pubmed/17191266?ordinalpos=17&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

If I wake up in the middle of the night while taking just 25mg of Seroquel, I know for sure I am drugged. After eight hours sleep, I have a small residual hangover which is easily knocked out with about three cups of coffee.
Take care,
Jedi

> approximately how long do you guys think I should take seroquel before going to sleep? I am using it for sleep but would rather just take ambien or lunesta and klonopin. but I am diagnosed bipolar.
>
> seems like the only thing seroquel has done to help that is make me a little more moody and flat/zombified but am going to give it a few more weeks to see if it shuts down the thoughts in my head/high energy to where i can sleep normally without anything...
>
> does seroquel work that way? can it so called "rebalance" a chemical imbalance and help me sleep again
>
> same thing happened with me years ago wear I all of a sudden got high energy and songs in head/racing thoughts and severe insomnia, and Effexor fixed it. but tried effexor again years later and had exact opposite affect of making everything worse
>
> so I am just worried Seroquel really won't "balance" what I need it to in the way that Effexor did
>
> can anyone take a minute to educate me or take a guess as to what might help? it would be VERY much appreciated!


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