Posted by JDx on April 16, 2008, at 10:12:05
In reply to Re: cognitive problems from solian, posted by undopaminergic on April 15, 2008, at 10:31:59
> Like you, I use methylphenidate (Ritalin, Concerta, etc.) and amisulpride (Solian), but I haven't noticed the memory impairing effect you describe.
>
> One possibility is that amisulpride and methylphenidate potentiate each other too much in some areas of the brain. In particular, the prefrontal cortex is sensitive to excessive dopamine (and noradrenaline) levels. There is evidence that alpha2A-adrenergic agonists are effective for treating such conditions. One such drug - guanfacine - has also proven useful for normalising some cognitive abnormalities in schizotypal personality disorder (a schizophrenia-spectrum disorder). Therefore, guanfacine may be worth a try (it's also good for ADHD).
>
> One study found memantine to be effective for negative (but not cognitive) symptoms in schizophrenia, so you may wish to look into that too.What side effects did you encountered from amisulpride? what are the daignosis your doctor perscribes you ritalin and amisulpride? anxiety and ADHD?
i am wondring what do i have - because if i have schizophrenia, this drug was suppose to inrease my cognitive abilities. and if my brain is normal , it doesn't suppose to do anything in that regard. same if i had adhd.
Before i started taking it i had extremly good photographic memory, i was best in my class in university and considered a genious of some kind..and now, I need to get help from other students in order to understang what is going on in classes,and i am sitting about 10 hours trying to read only a few pages in our work book=[about the medications you suggested,imo memantine could be a possiblity , mainly because it increases libido, and since i am taking ritalin i have no sexual motivation (solian doesn't help it, though risperdal and quetiapine did help)
poster:JDx
thread:823096
URL: http://www.dr-bob.org/babble/20080412/msgs/823587.html