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Re: Riluzole Lamictal questions » deniseuk190466

Posted by SLS on January 18, 2008, at 8:44:47

In reply to Riluzole Lamictal questions, posted by deniseuk190466 on January 18, 2008, at 7:44:36

Hi Denise.

For me, the addition of riluzole to Lamictal was not at all helpful. The only impact it made was on my precription plan. It is prohibitively expensive.

I don't want to get too theoretical here, but riluzole and Lamictal impact glutamatergic neurons in opposite ways.

1. Lamictal - glutamate release inhibitor.
2. riluzole - glutamate release enhancer.


I don't know whether these seemingly opposite mechanisms would effectively prevent a response.

I don't want to guarantee that the combination of these two drugs will produce no response or interact in ways that might actually make some people feel worse.


- Scott

 

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