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Re: Wistar Kyoto rats on Nicotine

Posted by linkadge on May 22, 2007, at 11:11:19

In reply to Re: Wistar Kyoto rats on Nicotine, posted by Nathan_Arizona on May 22, 2007, at 7:37:53

I've always thought that nicotine + low dose selegiline would be interesting.

For many smokers, nicotine alone is probably not enought to kick the habbit.

Nicotine is a very intersting substance, since in addition to its effects on dopamine, it also has effects on serotonergic neurotransmission.

Acutely, it decreases serotonergic firing in the dorsal raphai neucleus, supressing anxiety, in a manner perhaps similar to buspar.

For me, a low dose (gum) was sufficiant to help anxiety, significantly.

Linkadge



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URL: http://www.dr-bob.org/babble/20070509/msgs/758822.html