Posted by Quintal on April 22, 2007, at 16:58:23
I've been doing very well on this combo over the last few weeks and I seem to be getting better every day.
My full regimen is:
Tianeptine 12.5mg t.d.s.
Nicergoline 5mg b.d. (morning and night).
L-Tyrosine 500mg in the morning.
Agnus Castus 400mg (powdered fruits) b.d (morning and night).
Valerian Extract 300mg (equivalent to 1500mg Valerian root) at night.
Melatonin 9mg at night.
Paramol 7.46mg dihydrocodeine/500mg paracetamol, two tablets at night.
Nurofen Plus 12.8mg codeine/200mg ibuprofen, two tablets at night.My codeine use has decreased from four times daily to once at night. Since starting nicergoline I've found it makes me feel too tired and spaced out (and sometimes a little queasy) during the day. I actually feel better during the day for reducing the dose, but at night it helps me sleep peacefully. I'm not sure whether this is from nicergoline potentiating the effects of codeine (but hopefully not the paracetamol and ibuprofen :-), or simply that I no longer feel the benefit of the mood elevating effects vs. side effects now that I'm happy all the time?
I've also been doing a lot of exercise - up to five miles a day with my dogs, and of course the weather has improved and I actually have a tan for the first time in years (though I usually find the summer months the most depressing - bad hayfever, which has yet to make an appearance incidentally). Exercise has never been useful for me as a tool to actually lift my mood when I'm down, it often feels like masochism, but it does seem useful in maintaining a remission once the depression has lifted, and I usually find myself getting out more anyway once I'm feeling better.
My anxiety is now under control, and that isn't entirely down to the meds - I've been getting out more and forcing myself past barriers of fear, and usually they've dissolved (not gone away, but they're now permeable rather than the brick walls I'd made them by avoidance).
I'd like more info on nicergoline as the usual sources are a little sparing in detail. It certainly seems to be a peripheral vasodilator as some sources suggest - my hands and toes get very warm within half and hour of taking a dose.
Q
poster:Quintal
thread:752472
URL: http://www.dr-bob.org/babble/20070419/msgs/752472.html