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Re: Lamotrigine info requested

Posted by blueberry1 on February 15, 2007, at 19:19:02

In reply to Lamotrigine info requested, posted by linkadge on February 15, 2007, at 13:58:51

To get a feel for side effects maybe visit askapatient.com and remedyfind.com. Real users rate the drug and comment on side effects so you can get an idea of what is common and what happens once in a while.

Mechanism seems sketchy. I'm sure SLS or Hoover would know more so I hope they show up for this thread. At pubmed in some test with rats they determined it had some unknown noradrenergic and serotonergic action. Felt dopaminergic to me. Also some mention of maoi action, though that may not be significant enough for its effects.

I tried lamictal 3 times starting at 6mg for a couple days, 12.5mg for a couple days, and finally 25mg. To me it felt dopaminergic. It had a profound antidepressant effect within 36 hours. As I got up to 25mg I began getting tired and nervous at the same time which was weird. And I felt like I was getting more depressed real fast all of a sudden. Also gave me sexual side effectcs like an increased prolactin thing. Weird because I don't recall anyone ever talking about sexual side effects on lamictal and it isn't listed as a side effect.

Looking back, I think lamictal mixed badly with zyprexa. Every time I tried lamictal I was also on zyprexa, and also had either just finished some antidepressant or was starting a different one, so too many things were changing all at once. I still have some and plan to try it again. One person at remedyfind actually uses 6mg. That dose worked right away and the person stayed with that dose. I might use that same logic when I try it again. Whatever dose works, I'm staying with it.


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