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Re: Could someone explain what tianeptine is.... » maryhelen

Posted by psychobot5000 on December 9, 2006, at 16:13:11

In reply to Could someone explain what tianeptine is...., posted by maryhelen on December 9, 2006, at 15:23:40

It would be so appreciated it someone could explain to me what kind of medication this is.
>


Hi,

There are probably a few posts in the archives giving a good idea of this medication, but here are a few words:

It's a different sort of antidepressant, in that its primary mechanism of action is thought to be -increased- serotonin reuptake (the opposite of SSRIs). For some patients it has many fewer side-effects than other antidepressants. It also seems to reduce damage from stress-chemicals and has been shown to restore the growth of dendrites in the hypothalamus.

Structurally, it is a (modified) tricyclic, but generally lacks the antihistaminic, anticholinergic, and various receptor-blocking effects of the tricyclic class. It has other effects on monoamines though, such as boosting levels of dopamine (slightly) in the nucleus accumbens, through an unknown mechanism. It is closely related to amineptine (survector), but mostly lacks the stimulant effects of that drug.

It can be good for anxiety, but is (some think) not a very powerful antidepressant. However, it is very helpful for some patients, like me. It is not available in all areas of the world.


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poster:psychobot5000 thread:710441
URL: http://www.dr-bob.org/babble/20061206/msgs/711942.html