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Re: Ketamine study - is anything gona come of this » yxibow

Posted by zmg on December 1, 2006, at 15:21:07

In reply to Re: Ketamine study - is anything gona come of this » tessellated, posted by yxibow on December 1, 2006, at 4:37:21

Ouch. Party drugs is pretty hard label to shake. The kind of label that has a chilling effect on research (seem Maps vs. MDMA).

But the Ketamine research seems to be legitimate (honestly I think most research is legitimate and shouldn't be scoffed at because a drug finds it way into abuse, if you did that we wouldn't have a lot of existing medications!):

"The National Institute of Health News reports that a study of 18 patients led by Dr Carlos Zarate Jr. of the National Institute of Mental Health found that ketamine significantly improved treatment-resistant major depression within hours of injection. The improvement lasted up to one week after the single dose. The patients in the study were previously treatment resistant, having tried an average of six other treatments that failed. The importance of these findings was articulated by NIMH director Dr Thomas Insel: "To my knowledge, this is the first report of any medication or other treatment that results in such a pronounced, rapid, prolonged response with a single dose. These were very treatment-resistant patients." The researchers apparently attribute the effect to ketamine being an NMDA receptor antagonist. The study appears in the Archives of General Psychiatry. Those findings of Zarate et al corroborate earlier findings by Berman et all."


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