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Re: Phenobarbital for Anxiety » yxibow

Posted by ed_uk on October 26, 2006, at 13:50:19

In reply to Re: Phenobarbital for Anxiety » ed_uk, posted by yxibow on October 26, 2006, at 5:12:16

Hi J

>High or low potency (number of tablets and milligrams), its the dosage that works that counts, Klonopin or Valium really share similarities in long half lives (although Klonopin is usually dosed twice daily because the actually half life may be less than a day), although I swear now more by Valium for anxiety.

There is a tendency to prescribe diazepam at subtherapeutic doses. Clonazepam is more likely to be prescribed at doses that actually help. In this way, the high potency of clonazepam is relevent.

>There's also the slightly more esoteric Serax (oxazepam) which is another anxiolytic benzodiazepine (lower potency, higher dosing may be necessary but generally doesnt go through the liver.)

You certainly like the work 'esoteric' J! I think oxazepam is probably best reserved for elderly or debilitated patients who may have trouble metabolising other benzodiazepines.

Regards

Ed


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