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Re: Imipramine vs. Desipramine for Melancholic Dep

Posted by SLS on October 6, 2006, at 10:26:01

In reply to Re: Imipramine vs. Desipramine for Melancholic Dep » exquilter, posted by sregan on October 6, 2006, at 9:40:41

For me, imipramine and nortriptyline add a mood-brightening effect that desipramine lacks. Desipramine is energizing and alerting, but might lack something in the way of allowing you to feel good about doing things, motivation, interest, and reducing anhedonia. Perhaps this has something to do with its lack of serotonin reuptake inhibition. I prefer the way I feel on nortriptyline. I currently take 100mg. Remember, though, this is just the way I react to these drugs. Everyone is different.

Good luck.


- Scott

 

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