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Re: Can't Take it AnyMore ! Bad news - Good news » SLS

Posted by Jost on September 24, 2006, at 23:44:49

In reply to Re: Can't Take it AnyMore ! Bad news - Good news, posted by SLS on September 24, 2006, at 22:07:42

The Parnate study and another study are in the Sept. 2006 issue of the American Journal of Psychiatry (AJP).

The Parnate study, authored by Philip J. Mcgrath, of New York State Psychiatric Institute, is "Tranylcypromine versus Venlafaxine Plus Mirtazapine Following Three Failed Anti-depressant trials for Depression." AJP 2006, 163, 1519-1543.

The second study compared triiodothyronine (T3) vs lithium for a current AD. T3 outperformed lithium on numbers, but the difference again was not statistically significant. However, more participants in the lithium wing dropped out.

The article was supposed to be available as of Sept. 1, although I haven't checked Medline or the actual AJP website.

A third study from July 1, 2006 compared patients who had failed in two trials, who were allowed to switch to nortriptyline or mirtazapine. The results were 20% response to nortriptyline, 12% for mirtazapine, not statistically signficant. That article is by Maurizio Fava of Mass. General.

Jost


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