Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Can't Take it AnyMore ! Bad news - Good news

Posted by SLS on September 24, 2006, at 22:07:42

In reply to Re: Can't Take it AnyMore !!!!!!!!!!!!!!!!!!!!!!He, posted by Jost on September 24, 2006, at 20:51:20

> They published several papers, but overall, apparently, non-responders don't do well after earlier rounds of the study.

I guess we are just going to have to do better, then.

TRD is TRD. That's the bad news.

We have the advantage of using many more drugs in different combinations. I wonder how many more people would get well if they were to add low-dose lithium to their treatment (300-600mg). It is the forgotton miracle drug. Lamictal might be an alternative as an augmenting agent. We have a couple of people who found their miracle pill in Lyrica.

Do you see why it becomes such a good idea to bring as many drugs to market as possible, regardless of their similarity? Creating treatments for people with TRD is sometimes evidence-based and sometimes closer to alchemy. Clinical experience has demonstrated that an individual can respond quite disparately to different drugs within a class. The more SSRIs, the better, as long as it doesn't prevent or delay the development of novel drugs. Let the market weed out the duds. I'm amazed that Ludiomil (maprotiline) is still on the market. That's one drug I haven't tried yet. It's supposed to be a piece of crap, but obviously it works great for some people. I hope it stays on the market. It will give me one more ray of hope to keep me going if I near rock-bottom. That's the great thing about this whole thing - uncertainty. You can't be certain how you are going to respond to anything. There is always the chance that you will respond therapeutically to just about anything. That's the good news.

Where did you find the Parnate study?

- Scott




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:SLS thread:688552