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Re: Dopaminergics, amineptine, addiction

Posted by linkadge on August 28, 2006, at 21:07:42

In reply to Re: Dopaminergics, amineptine, addiction, posted by psychobot5000 on August 28, 2006, at 20:13:10

But, ritalin works for ADHD not because it increases dopamine in the pleasure centres of the brain, but because it increases dopmaine in the frontal cortex.

The activity of dopamine depends on the receptor and on the region of the brain. I don't think that dopamine agonists like mirapex are acutely rewarding, but I don't know I havn't taken one.

The only antidepressant I found that was acutely rewarding was Parnate. Right after the first dose I felt warm pleasurable sensations all over my body. I imedately became more sociable, and had a mild overall sence of well being. That being said, it was the only one that made my mildy psychotic.

The antidepressant effect of the drug was probably sufficiant to supercede any desire to increase the dose, but I can kinda see how this one could be abused.

Linkadge



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URL: http://www.dr-bob.org/babble/20060825/msgs/681008.html