Posted by SLS on July 17, 2006, at 22:01:03
In reply to Re: couldn't have said it better myself, posted by linkadge on July 17, 2006, at 21:32:49
> "and the placebo response overall appears to have increased over time"
>
> Perhaps, but what magnitide are we talking about. There are no numbers. It could have increased an average of 2% for all I know.
>
> In one sense I can see drug responces in the past as being stronger since the TCA's are more effective drugs.
>
> I would need some numbers that show how the placebo response has increased significantly.
>
> Placebo response could have been lower in the past too due the the weaker "establishement" of AD's in the past.
The numbers are all there. All you have to do is go to the library and pull out the journals. I started doing that in 1982. That's how I knew the numbers had changed even before I encountered the literature I cited along this thread. I witnessed the changes in placebo response over a 25 year period. It has been far more than 2 percent.Currently marketed antidepressants work significantly better than our most recent clinical trials indicate.
- Scott
poster:SLS
thread:662854
URL: http://www.dr-bob.org/babble/20060717/msgs/667893.html