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Re: one thing Prozac does, not chemical imbalance » linkadge

Posted by Larry Hoover on May 29, 2006, at 21:27:48

In reply to Re: one thing Prozac does, not chemical imbalance » Larry Hoover, posted by linkadge on May 29, 2006, at 20:14:15

> >The dose was only 110 times the human dose
>
> I think that study tested several doses, one showed corscrewed receptors at lower doses as well.

I don't think that's the case. I just looked and found one article, Kalia et al, (2000). She remarked, at the time, that she planned to do follow-up reasearch in which she would "reduce the dose to a much lower one, only 10 to 30 times the normal human dose...." and observe rats for 6 months to a year before examining their brains.

As the original was published in 2000, and no follow-up has yet been published, what can we conjecture from that? I reiterate, the preliminary research was done at doses at least two orders of magnitude greater than that to which humans are exposed. Do that with table salt, and you've got a dead rat.

> The thing about this study was that the changes happenened in mice within a very short period of time.

Brains are not time machines.

> The researchers were questioning whether lower doses for longer periods of time might have the same effect.
>
> Linkadge

I thought I'd found a link to the full-text, but the link was broken and I can only read the first page. http://www.maps.org/publications/2000_kalia_1.pdf

Anybody got another?

Lar

 

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poster:Larry Hoover thread:649281
URL: http://www.dr-bob.org/babble/20060525/msgs/650256.html