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Re: Coreg: insulin-sensitizing properties? » ed_uk

Posted by saturn on May 3, 2006, at 22:13:42

In reply to Re: Coreg: insulin-sensitizing properties? » saturn, posted by ed_uk on May 3, 2006, at 9:59:30

> Hi Saturn

Hey back Ed!

> Perhaps surprisingly, cardioselective beta blockers such as atenolol, metoprolol and bisoprolol are actually very useful in diabetic patients! Here is some information......
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12652116&query_hl=5&itool=pubmed_docsum

I really appreciate the link--this is very helpful info.

> Non-cardioselective beta blockers are in some cases more problematic in diabetic patients - they can mask the warning signs of hypoglycemia.


> >I had thought that all beta blockers carry the risk of insulin resistance and diabetes. Does this mean that Coreg does not?
>
> Apparantly :) I've read that before. It may be due to carvedilol's activity as an alpha blocker. Although carvedilol is not cardioselective, it is clearly a useful drug for some patients with diabetes complicated by hypertension, angina or heart failure.

Perhaps you could get the best of both worlds by taking a cardioselective beta blocker and also an alpa blocker.

I'm going to talk w/ my doc about these options. I'll let ya know how it goes. By the way, how goes it w/you?

Take care,

"sat"


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