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Re: Coreg: insulin-sensitizing properties? » saturn

Posted by ed_uk on May 3, 2006, at 9:59:30

In reply to Coreg: insulin-sensitizing properties?, posted by saturn on May 2, 2006, at 19:13:43

Hi Saturn

Perhaps surprisingly, cardioselective beta blockers such as atenolol, metoprolol and bisoprolol are actually very useful in diabetic patients! Here is some information......

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12652116&query_hl=5&itool=pubmed_docsum

Non-cardioselective beta blockers are in some cases more problematic in diabetic patients - they can mask the warning signs of hypoglycemia.

>I had thought that all beta blockers carry the risk of insulin resistance and diabetes. Does this mean that Coreg does not?

Apparantly :) I've read that before. It may be due to carvedilol's activity as an alpha blocker. Although carvedilol is not cardioselective, it is clearly a useful drug for some patients with diabetes complicated by hypertension, angina or heart failure.

Regards

Ed



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