Posted by yxibow on April 28, 2006, at 1:41:36
In reply to Re: Klono depressing. Need long benzo not depressi » yxibow, posted by ed_uk on April 27, 2006, at 16:19:46
> Hi Yxi,
>
> Flunitrazepam (Rohypnol) is a long-acting hypnotic. Its effects tend to persist the following morning. Triazolam (Halcion), as you said, has a short duration of action.Yes... I inadvertently included Rohypnol in that group... you're right. But Halcion is very short. It got bad press for people supposedly doing wierd and violent things on it at one point but the half life is so short that the likelihood of causality is hard to prove. It is still sold here.
>
> I did some research RE the metabolism of diazepam (Valium). It turns out that temazepam (a metabolite of diazepam) does not contribute significantly to the clinical effects of diazepam, since it is excreted at approximately the same rate as it is generated, and is therefore almost undetectable in the blood.That would make sense, yes
>Desmethyldiazepam is the only metabolite of diazepam which is clinically important.Interesting... I was about to say why didn't they patent extend Valium but they did... in some obscure countries, not here anyhow... Nordazepam
http://en.wikipedia.org/wiki/Nordazepam
-- tidings
Jay
poster:yxibow
thread:636282
URL: http://www.dr-bob.org/babble/20060423/msgs/637732.html