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Re: Another drug failure linkadge

Posted by SLS on April 22, 2006, at 14:35:49

In reply to Re: Another drug failure, posted by linkadge on April 22, 2006, at 12:26:14

> Nortryptaline, lamictal, abilfy seems to be a good base.

I think so too.

> Have you tried omega-3 augmentation?

Yes, but not with the combination of things I'm on right now.

> I'd add around 1 gram of EPA, and perhaps some folic acid. Zinc too, can augment antidepressnat responces. You could always try inositol. It acts as a second messenger to the noradrenergic system.

I still have some fish oil, folic acid, and inositol in my box of rejects. The fish oil had some positive effect at first.

> (Although, inositol and nortryptaline might have mania writtain all over it!)

I wouldn't mind becoming manic because for me it is so easily treated with valproate or Zyprexa.

> How did you fair on SSRI's?

Zoloft produced a brief antidepressant response while I was taking imipramine and Lamictal. I think it would be justified to try it again with the Wellbutrin.

> The combination of sertraline and a nortryptaline would be like a triple uptake inhibitor.

I hope my doctor allows me to take all three antidepressants at the same time (nortriptyline, Wellbutrin, and Zoloft).

I tried Prozac, but only at 20mg. I also tried Paxil 30mg and Lexapro 20mg. I have not tried Luvox nor Celexa. I like Zoloft because it wasn't bad with side effects. I've also tried Effexor and Cymbalta. The pattern of response is always the same. I will start to improve during weeks 2-4 and relapse within a week.

You really think Zoloft + TCA is that potent? Hmmm. That might be a way to go. I would want to keep the Wellbutrin, though.

They say that if you throw enough sh*t against the wall, some of it is bound to stick.

- Scott




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