Psycho-Babble Medication | about biological treatments | Framed
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Re: no side effects=way cool!!!!!!!!!!!

Posted by linkadge on April 11, 2006, at 15:20:09

In reply to Re: no side effects=way cool!!!!!!!!!!! (nm), posted by ravenstorm on April 11, 2006, at 11:38:34

Even if Ensam metabolizes to amphetamine I don't know the degree to which this figures into the antidepressant effect. Kindof like how nicotine often doesn't fully replace the effects of smoking (ie smoking affects MAO levels)

I think that emsam should be affecting MAO-A at these doeses. Of course it will affect MAO-B more, but the ratio may be benificial for certain types of depression.

MAO-B is responsible for demeniating PEA, a trace amine which seems to have significant antidepressant effect. The combination of selegeline and phenylethylamine has been proven similar to imipramine in a few studies. So there is possible room here for augmentation if necessary.

The combination of ENSAM and exercise might be very significant. Exercise causes a significant release in the levels of phenylethylamine. In some people 45 minautes of exercise can increase PEA output by something like 7x. Taking ensam would reduce the level of PEA metabolized. Be carefully if you have paranoid schizophrenia!
Very high levels of PEA have been found in hyperreligiosity (I will look for that study). So be carefull if you start to feel an intense need to start preaching on the streets. (Not that there is anything wrong with that ~(?))

I remember combining exercise and parnate, and that was very strong. I remember after about 30 minautes of jogging I would look around and everything would look *totally* different. It felt strange and otherworldly, like I had entered a different dimention. Everything looked so foreign, I had seen that lamppost a million times yet never like this. It literally turned on circutry that I didn't know existed. It was intense, kindof scarry too. (Now I know everybody isn't like me)

Exercise exercise with caution :)





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