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Re: Drugs versus Psychotherapy - Backlash?

Posted by SLS on April 8, 2006, at 19:01:56

In reply to Re: Drugs versus Psychotherapy - Backlash?, posted by linkadge on April 8, 2006, at 16:46:21

> > Despite all of my treatment failures, I still >believe that, in capable hands, over 75% of MDD >people will respond well to the drugs we already >have available, especially when used as part of >a multimodal approach that may include >psychotherapy, nutrition, and even exercise.

> I don't think that drugs are responsible for getting 75% of people better. Clinical trials certainly don't demonstrate this,

What I attempted to convey is that an effective treatment regime can be produced for 75% if one were to use every drug currently available alone or in combination. Very few trials have been designed to study this.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15960558&query_hl=33&itool=pubmed_docsum

That's 65% using only 3 antidepressants monotherapeutically.

> and even less when you remove possible effect of placebo,

The magnitude of the placebo response varies inversely with the severity of the depression being used as inclusion criteria.

http://ajp.psychiatryonline.org/cgi/content/full/157/3/327


- Scott

 

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