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caffeine and opioid receptors

Posted by pseudoname on March 7, 2006, at 10:00:33

In reply to Re: re..Caffeine and P450, posted by willyee on March 7, 2006, at 1:06:21

Last year when I tried the opioid receptor-blocker naltrexone, the morning after my first dose, instead of jonesing for coffee as usual, I had absolutely no interest in caffeine.

When I tried a couple small glasses of Diet Coke after that (maybe 25 mg caffeine), I felt a slight version of the usual warm/fuzzy effect, but with no interest in escalating it. Usually I want more more more caffeine.


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