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Re: NARDIL + PARNATE! » SLS

Posted by Chairman_MAO on March 3, 2006, at 15:29:42

In reply to Re: NARDIL + PARNATE!, posted by SLS on March 2, 2006, at 8:37:42

I think serotonin syndrome, thrombocytopenia, and perhaps something completely idiosyncratic are the biggest risks. The risk of stroke is there, but these drugs cause some degree of platelet derangement. Adding them together both at full therapeutic dosages seems like too big a risk.

There are quite a few case reports of thrombocytopenia from excessive MAOI intake.

Also, the MAOIs themselves do not forget are metabolised by MAO. :)

The GABA-T inhibiting metabolite of phenelzine I believe is formed by MAO-B.


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URL: http://www.dr-bob.org/babble/20060227/msgs/615475.html