Posted by linkadge on December 10, 2005, at 14:36:35
In reply to Re: Dr. Tracy on SSRIs.. » linkadge, posted by Larry Hoover on December 10, 2005, at 13:51:28
"Elevated serotonin is not the problem, because there is no such condition."
Elevated serotonin is implicated in a number of conditions. If you visited the Buspar website a year ago, it would have told you that anxiety is related to elevated serotonin.
There is a lot of research that shows that anxiety may actually be related to high serotonin levels. Serotonin can be anxiogenic. Hence the SSRI start up anxiety, and GI effects that don't go away for many people.
Hinting that high serotonin leads to agression is not unfounded. Many doctors have noted that artificially increasing serotonin can lead to emotional indifference. Studies on animals sometimes show similar results, ie. MAO-A knockout mice are unusally agressive.
"Serotonin is a precursor to melatonin, so how could it suppress melatonin? What is premature aging? She cannot bring these ideas into a coherent whole. "
I don't know, you tell me. Most of the SSRI's decrease melatonin concentrations. Infact, melatonin administration reduces the antidepressant effect of fluoxetine. In the night time melatonin levels are at their highest, and serotonin levels drop. SSRI's supress melatonin production via agonism at the 5-ht2a receptors.
The 2a blocking antidepressants tend to increase melatonin production.
Lowering melatonin levels will lead to premature aging.
The connection to LSD is also not unfounded. I experienced visual halucinations on SSRI's. A number of other people on this board have too.
Prozac seems to have the highest propensity to do this, since it seems to more strongly agonize the 5-ht2a receptor, via 5-h2c blockade.
She is attempting to make these connections, so that we have a basis for understaning the kind of behavior that they can produce.
I have what I call APPD, "antidepressant induced perceptual disorder"
Linkadge
poster:linkadge
thread:587690
URL: http://www.dr-bob.org/babble/20051203/msgs/587802.html