Posted by ed_uk on November 26, 2005, at 13:31:57
In reply to Re: When the options are gone? » Peace2U, posted by Bob on November 26, 2005, at 2:18:43
The MAOIs are not anticholinergic as such: unlike the tricyclics they do not block cholinergic receptors directly. They do often cause side effects which resemble anticholinergic symptoms though, probably because of their noradrenergic properties.
>Interesting, as I was under the impression that the tolerability between the two classes was not all that different.
The MAOIs and tricyclics are very different. Because of this, some people have more side effects on tricyclics whereas other people have more side effects on MAOIs. Your experience with tricyclics cannot be used to predict whether you will have side effects from MAOIs. In addition, Nardil is quite different to Parnate. People often report that they find them very different, both in terms of therapeutic effects and side effects.