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Re: SSRI + Low Dose Antipyschotic for TRD

Posted by blueberry on October 18, 2005, at 18:43:41

In reply to SSRI + Low Dose Antipyschotic for TRD, posted by CK1 on October 17, 2005, at 22:54:37

My doc also combines antipsychotics with antidepressants in many patients. Somehow the combinations synergistically release more dopamine and norepinephrine.

I was on 20mg prozac and 5mg zyprexa for 5 years. Five good years. It did eventually begin to fade a bit and then I had a breakthrough manic episode, so now I'm on the hunt again. But if you are looking for something that can work good and work for a long time, APs + ADs in my experience are good combos. Keep the AP dose low to keep any longterm risks at a bare minimum. I had no problems in 5 years in terms of diabetes or TD or anything related to APs.


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