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SSRI + Low Dose Antipyschotic for TRD

Posted by CK1 on October 17, 2005, at 22:54:37

Hi Peep,
I just started Nardil a few days ago and I'm feeling better already, but my doctor thinks I have soft/fuzzy bipolar since my Paxil pooped out after a few years and my response to SSRI's since then hasn't been good. I haven't responded to 4 straight SSRI's since, my friend, Paxil left me high and dry!

He believes that even if I get a great response from Nardil, it might poop out just like Paxil. According to him, SSRI's only poop out because of bipolar disorders and long term reduction of dopamine.
If Nardil flops (which it better not!), he thinks putting me back on Paxil and adding Seroquel or another AP will bring Paxil back to life so to speak. He's added antipsychotics to an SSRI for many of his patients whose drugs pooped out on them and most seem to regain their response long term.
Does anyone have experience with the SSRI + AP combo? It seems interesting! I like what I see! Antipsychotics seem like very cool drugs, despite the TD thing.

My new doc and I are looking long term. I don't like this "doing great for a year or two and then back to square one" crap. Getting better and then getting worse again isn't cool in my book. I want to stay "up." SSRI + Seroquel, Zyprexa, etc. Tell me more, give me stories, help me out.

Peace people.
ck


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