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Sleep deprivation elevates Inhibin B levels!

Posted by WeeWilly on August 2, 2005, at 10:23:04

In reply to Re: why can't we mimic sleep deprivation, posted by linkadge on August 1, 2005, at 17:40:27

Back in 1987 it occured to me that Inhibin might be a factor in my own mood disorder. As the years have gone by I have followed the progress in the understanding of Inhibins function in the CNS. When it was first isolated in 1985 it was thought to have a very small role. It is now known to have wide rangeing functions. Just last year a study headed by Andrew Shelling at the U of NZ, identified a mutation in some individuals inhibin gene to cause mood problems along with other disabilities. Unfortunatley this research group is focused on the reproductive problems that this mutated gene causes. Hopefully another research group with a goal of understanding Inhibins effect on mood will put 2 & 2 together.
I have had my Inhibin level measured before and after sleep deprivation and it definately elevates. The endocronologist who allows me to have these tests done ( at considerable expense), does'nt discount my theory alltogether. But he expresses what I allready know that being, studies have not been done yet to give us understanding of Inhibin and its many functions in the CNS. Best Wishes




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