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Re: Going back on Anafranil (Clomipramine) :-/ » rod

Posted by SLS on July 12, 2005, at 10:53:06

In reply to Re: Going back on Anafranil (Clomipramine) :-/ » SLS, posted by rod on July 11, 2005, at 17:35:58

Hi Roland.

Where are you living right now? I know metyrapone is available the UK. If you want to experiment with cortisol / HPA stuff, you might want to try taking ketoconazole to see if it helps at all - even if only for a short time.

Our illnesses seem to present very similarly. Maybe I'll just let you figure it out for the both of us and have you tell me what to do. :-)

I am amazed at the rate at which you have lost access to the older medications. It is scary. I hope it doesn't happen in the US. It will be very interesting to see how you react to agomelatine. If you respond well to it, I'll have to see what I can do to get it. I once tried taking melatonin. I'm pretty sure it made me feel moderately worse. I didn't take it for too many days. The deterioration in my condition was too obvious.

> And I have taken most of the drugs in various combinations. Well, do you want me to write all combinations too?

I doubt that would be necessary. I'll just make believe you've done most of the same things that I have.

Anafranil + lithium sounds interesting. If I understand you correctly, you have not yet tried lithium?

For me: Parnate + desipramine (had best response to these drugs ever. Was almost in clinical remission). But my supersmart doc wanted to put me on Prozac.

Sound familiar? I never responded to this same combination again.

> Scott, since you are on Parnate, do you find it having an impact on your "core symptoms"?

No. It gives me more mental energy to work with, but that's about it. Part of that includes more energy to talk, but not an increase in sociability. Adding nortriptyline helps a bit in that aspect. I found Nardil to be better for mood-brightening and socialability, but it leaves me with very little once it poops out.

> Right now, I havent chenged anything yet. I somehow think about driving to Slovakia or the other eastern european countries to get some PARNATE!? if available.

You can work with Parnate more easily. You can go higher in dosage with reduced side effects. You can add things like nortriptyline, bupropion, and amphetamines to it.

If you have never tried Parnate or Nardil, you really should consider making it your next move. Just be prepared to deal with insomnia. Insomnia is a difficult side effect to deal with, but should be dealt with agressively and not be allowed to determine the course of treatment. I found that insomnia with MAOIs was a good sign for me that I would respond to it.

How did Lyrica affect you? What were you taking along with it?


- Scott

 

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