Posted by SLS on June 17, 2005, at 17:04:00
In reply to Re: Is There A Magic Pill? » RetiredYoung, posted by ed_uk on June 17, 2005, at 16:34:02
> Hi Jim :-)
>
> >Pamelor worked great for me for depression years ago; until my doctor realized that my resting pulse was 115 and I would burn my heart out with long term use of Pamelor.
>
> I've never been convinced that TCA-induced sinus tachycardia was harmful to the heart,Me neither.
One thing that offsets the accelerated heart rate is the reduction in the load that the heart must work against. It is the NE alpha-1 antagonist properties of TCAs that dilates blood vessels to allow for this.
> I don't think there's any evidence that it is. My resting heart rate was about 110 when I was on lofepramine.
Mine has been over 100 on all of the tricyclics I have been on. Neither my doctors nor I have had any concerns about this.
> Don't rule out going back on Pamelor some day!
It would be a tragedy to rule out an effective drug on the basis of an acceptably accelerated heart rate. TCAs are supposed to do this.
> You could always add a small dose of atenolol if you were concerned. Atenolol would slow your heart rate.
That's a great idea. Of course you can always see if pindolol lives up to its proposed action as an augmentor of antidepressants while slowing the heart.
- Scott
poster:SLS
thread:514026
URL: http://www.dr-bob.org/babble/20050617/msgs/514426.html