Posted by Elroy on May 27, 2005, at 23:45:45
In reply to Re: Severe Anxiety, Moderate Depression High Cortisol, posted by sabre on May 27, 2005, at 2:23:50
No, have not tried beta blockers.
Not sure how accurate they are (as levels of most hormones can cycle from highs to lows throughout the day), but I had one blood test that showed levels of dopamine, epinephrine, and norepinephrine.
The dopamine was somewhat low, the epinephrine was noticeably low and the norepinephrine was extremely low (well below bottom of normal range). My pdoc was stunned as she ahd felt with my high anxiety that those adrenaline hormone levels would be off the chart.... on the HIGH side! (My pdoc had not ordered that specific test, my endo had to see if I had a Pheo tumor - which can cause severe anxiety... but I had naturally shared the results with my pdoc).
So not sure if beta blockers would be a good idea if those levels are alerady that low. Also have normally lower blood pressure and not sure what effect beta blockers would have on that.
Interestingly NE boosters such as Effexor or Cymbalta make both my anxiety and physical symptoms MUCH worse).
And obviously would want to stay away from NARIs like reboxetine which raise cortisol levels.
Likewise with SSRIs... they have either been too stimulating and worsened the problem or simply provided nothing but side effects.
X
X
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X> Hi Elroy
> Beta blockers promote the reuptake of noradrenaline.
>
> NARIs like reboxetine, inhibit the reuptake of NA which raise the levels of plasma and salivary cortisol.
>
> Have you tried beta blockers?
>
> Read these:
>
> Reboxetine acutely stimulates cortisol, ACTH, growth hormone and prolactin secretion in healthy male subjects.
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14604600&query_hl=5
> Sex differences in cortisol response to reboxetine.
>
> I hope it helps
> Sabre
poster:Elroy
thread:502852
URL: http://www.dr-bob.org/babble/20050527/msgs/504021.html