Posted by flipsactown on April 9, 2005, at 18:35:48
In reply to Re: Oxycontin for mental health....WOW!!!!!!!!!, posted by Larry Hoover on April 9, 2005, at 18:19:16
Lar,
>
> Your absence of withdrawal leads me to believe that perhaps your 2D6 enzyme (the enzyme in question) doesn't work at all, and you got a pure codeine effect. If I'm not mistaken, oxycodone also is activated by that same enzyme. (Have I got that right, ed?) Total dysfunction of 2D6 might happen in 0.1 to 1% of people.
>
That sure sounds logical to me!
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> What most amazes me, really, (I know you said nothing about this at all) is that you could take that dose of codeine and still have bowel movements. Codeine is very constipating at high doses. Maybe the worst of them all, on a mg per mg basis? If not the worst, it's near the top of that infamous list.
>
I was only slightly constipated initially. I imagine after that my system totally adjusted to it. When I tried MSContin, I was extremely constipated.
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> Thanks for your input. It's really important to try and understand just how variable the effects of drugs really are.
>
Your welcome. That is the very reason I always include in my post that "It is my personal experience."FST
poster:flipsactown
thread:479222
URL: http://www.dr-bob.org/babble/20050408/msgs/482132.html