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Re: Never parnate with an SSRI » ixus

Posted by smith562 on April 8, 2005, at 5:51:58

In reply to Re: Why not Parnate? » smith562, posted by ixus on April 8, 2005, at 4:27:51

> Selegiline is more activating and anxiogenic than tranylcypromine.
> /ixus

I know they are both non-hydrazine MAOIs and can be anxiogenic for some ... selegiline does metabolize to amphetamines. The problem with parnate was that I would never add an SSRI and risk serontonin syndrome/death. The data with selegiline at 10mg or below suggest it is fairly safe (thousands of parkinson's patients get selegiline and an ssri every year), although no guarentees.

I am hoping low dose zoloft and klonopin will offset any anxiety induced by selegilne. Hopefully someone out there has maybe tried this and can give me feedback.

Thanks Ixus! Hope you are well. Please keep the post coming!

Smith


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