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Re: I'm here Sarah T.

Posted by SLS on March 25, 2005, at 5:27:11

In reply to Re: I'm here SLS, posted by Sarah T. on March 24, 2005, at 20:33:44

Hi Sarah.

> > > > > This might not be a bad idea. Thanks. I'll probably stay away from memantine for awhile, though.

> Hi Scott. When you started Memantine, was it for augmentation of something you were already taking?

Not specifically, but I was taking imipramine, Lamictal, and Abilify at the time. The addition of 20mg memantine worked for about 2 weeks, then fizzled out. Raising the dosage to 40mg didn't serve to recapture the antidepressant response. I experienced no side effects during this first trial. It was during a more recent trial in combination with Parnate that memantine treated me nastily.

> Do you know whether Memantine might reduce and/or reverse tolerance that has already developed?

There is more evidence that this is true of opioids than of stimulants. However, I have seen here anecdotal reports of limited success using memantine to help minimize tolerance to Adderall.

> > My doctor would like me to try acetyl L-carnitine. I'm thinking of adding to it folate and DHEA.

> Can you tell me why your doctor is suggesting you try acetyl-L-Carnitine?

My depression is so anergic, that my doctor thought that strategies to treat CFS (chronic fatigue syndrome) might help. Carnitine is essential for mitochondrial energy production. I experience more mental fatigue than physical fatigue. I think this is why he chose acetyl- over propionyl- carnitine.

Since I'm already going to be in the vitamin shop, I might as well add the folate and DHEA while I'm there. I already have the B-complex. I still have yet to determine dosages. 2 grams per day sounds about right. I don't have a clue as to how expensive the stuff is.

- Scott




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