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Re: Clonazepam (Klonopin) - steady state concentration

Posted by sdb on March 24, 2005, at 22:40:32

In reply to Re: Clonazepam (Klonopin) - steady state concentration, posted by missamor on March 22, 2005, at 14:49:11

I have the interesting reaction that Klonopin 2mg once daily without pretreatment cause *more anxiety* and what is normal with benzos some sedation, sleepiness and muscle relaxion. The anxiety is less when i take the Klonopin for a few days. This would prove when plasma levels accumulate-> it causes some more efficacy. But I cannot support that Klonopin immediately relieves anxiety.

Does somebody have the same experience?

During a week on Klonopin i had no problems with longterm memory but a little bit with short term memory (with alcohol its the same). Klonopin sedates (I only took it for one week), but i cannot say it would cause depression. But its definately not energizing.

Does somebody have problems in memorizing things with Klonopin (learning facts)?

A bad sideeffect is a loss of libido. Perhaps there is the possibility to combat this with bupropion (i have never taken it) or even tadalafil. Buspirone does nothing, remeron does a lot for libido but i have bad sideeffects (sedation...), trazodone is the best because it improves libido and erection (feeling like a bull) but i feel bad with that drug, cannot concentrate anymore. Some persons have the opposite therefore positive effects for libido (a guy called Rick). But studies and I cannot support that. Every is different. Perhaps I should take the drug longer than seven days and the sideeffects could turn in the positive opposite way.

I have once taken 2mg Xanax retard and I think it only sedated me.

The best I have tried for physical anxiety are betablockers. Nadolol, oxprenolol (slow) and pindolol for short term does a lot. The rest of the betablockers are not that good. Above all propranolol (sedation, loss of libido etc.) and beta1-selectives like atenolol (only reduces exercise tachycardia mediated through nervi cardiaci, for isoprenaline (b1/b2 agonist like epinephrine) it does almost nothing. Only good in high dosages. I only take betablockers currently.

These are some experiences.

Every comment or all answers to questions are welcome!

to ed: I come from the eurozone.




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