Posted by ed_uk on February 13, 2005, at 10:12:55
In reply to Re: Effexor: Marketing Ploy » ed_uk, posted by Nixon on February 13, 2005, at 9:39:12
Hi,
Depakote sometimes produces a slight reduction in the plasma concentration of an active metabolite of Trileptal. Trileptal does not produce any significant change in the plasma concentration of valproate (Depakote). I don't think you need to worry about Depakote interacting with Trileptal. You might notice some increased side effects while you're on Depakote and Trileptal, drowsiness/cognitive impairment may be a problem, don't drive unless you're sure you're up to it.
Have you asked your doctor to let you try Trileptal? What does s/he say? Are you going to add Trileptal while you're still taking Depakote and then withdraw the Depakote when you're on a therapeutic dose of Trileptal? Perhaps you could reduce the Depakote to 125mg/day before stopping it completely.
Ed.
poster:ed_uk
thread:456946
URL: http://www.dr-bob.org/babble/20050212/msgs/457113.html