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Re: The Opiate Trials jerrympls

Posted by jujube on January 10, 2005, at 23:37:01

In reply to The Opiate Trials, posted by jerrympls on January 10, 2005, at 19:46:03


I am so happy that you have found a pdoc that is listening to and working with you to try to put in place an effective treatment plan. It must be such a relief to you after struggling for so long. You sound more optimitic than you have in a while, and it is so nice to hear that sense of optimism in your post.

I would be very interested in hearing about your progress.

Good luck to you Jerry. Take good care.


> So, my pdoc and I had a couple plans:
> PLAN A: Add metyrapone to Lexapro (as per recent studies) to see if it would help.
> PLAN B: If plan A failed, then augment with an opiate.
> Well, unfortunately - and somewhat fortunately - Novartis will only dispense Metyrapone to those with Cushing's despite recent studies finding it helps with depression. So, my pdoc said "Let's go to Plan B."
> So, after providing him all I could find on the use of opiates for depression and after his own research he agreed to do a "trial" of the addition of an opiate to my current cocktail. Of course we went over all the precautions, etc and made a "contract" of sorts as far as a) seeing each other weekly, b) dosage range c) watch for tolerance, etc....and some other details.
> So tomorrow I start Oxycodone CR (Oxycontin 10mg) once daily.
> I'm happy that I have a doc who would even consider this none the less actually DO it. All I've been aslking for is a fair trial on an opiate for my TRD - and if it doesn't work or poops out in a week - then I guess we move on to something else. But I'm glad to be able to try it. Hopefully it will work long-term and I won't have problems with tolerance (as some studies have shown).
> So, if anyone's interested I'll keep posting my progress??
> Jerry




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