Posted by jerrympls on January 10, 2005, at 19:46:03
So, my pdoc and I had a couple plans:
PLAN A: Add metyrapone to Lexapro (as per recent studies) to see if it would help.
PLAN B: If plan A failed, then augment with an opiate.
Well, unfortunately - and somewhat fortunately - Novartis will only dispense Metyrapone to those with Cushing's despite recent studies finding it helps with depression. So, my pdoc said "Let's go to Plan B."
So, after providing him all I could find on the use of opiates for depression and after his own research he agreed to do a "trial" of the addition of an opiate to my current cocktail. Of course we went over all the precautions, etc and made a "contract" of sorts as far as a) seeing each other weekly, b) dosage range c) watch for tolerance, etc....and some other details.
So tomorrow I start Oxycodone CR (Oxycontin 10mg) once daily.
I'm happy that I have a doc who would even consider this none the less actually DO it. All I've been aslking for is a fair trial on an opiate for my TRD - and if it doesn't work or poops out in a week - then I guess we move on to something else. But I'm glad to be able to try it. Hopefully it will work long-term and I won't have problems with tolerance (as some studies have shown).
So, if anyone's interested I'll keep posting my progress??
Jerry
poster:jerrympls
thread:440311
URL: http://www.dr-bob.org/babble/20050108/msgs/440311.html