Psycho-Babble Medication | about biological treatments | Framed
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Re: Never underestimate the pain of severe akathisia

Posted by ed_uk on December 12, 2004, at 20:02:37

In reply to Never underestimate the pain of severe akathisia, posted by ed_uk on December 12, 2004, at 19:42:12

Delayed akathisia and suicidal attempts following epidural droperidol infusion--a case report.

Hung YC, Ho YY, Shen CL.

Department of Anesthesiology, Ton Yen General Hospital, Hsin Chu, Taiwan, R.O.C.

Epidural administration of droperidol has been used to prevent postoperative nausea and vomiting (PONV) caused by opioids, but the adverse reactions were relatively neglected. We present a patient who received patient-controlled epidural analgesia (PCEA) with bupivacaine-morphine-droperidol mixture for one and half days following hemorrhoidectomy, developed paroxysmal adverse reactions of akathisia, dysphoria, and suicidal attempts 3 days after the initiation of the treatment. The use of droperidol in PCEA for prevention of nausea and vomiting therefore needs to be re-evaluated according to the serious side effects occurring in our case.

And finally, another reason to initiate AP treatment with low doses......

J Clin Psychiatry. 1987 May;48(5):207-8.

Very low-dose neuroleptic treatment in two patients with agitation associated with Alzheimer's disease.

Risse SC, Lampe TH, Cubberley L.

Two agitated patients with Alzheimer's disease who either failed to respond or worsened with conventional low-dose neuroleptic and other pharmacologic treatment are described. Both patients demonstrated sustained improvement with very low-dose neuroleptics, one with haloperidol 0.125 mg and the other with thioridazine 5 mg.





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