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Re: Saw pdoc - didn't go as I had hoped - scared » jboud24

Posted by jujube on November 6, 2004, at 15:19:18

In reply to Re: Saw pdoc - didn't go as I had hoped - scared, posted by jboud24 on November 4, 2004, at 10:03:43

Thanks Justin. I have been putting off starting the Anafranil for the past few days. I will probably start on Monday. I'm still a little nervous about side effects, but I guess I'll never know until I start taking it. If the side effects are unbearable, I will stop. But, I will try to give it at least two weeks before I give up. I don't have anything to lose, except this misery of a depression. I'm going to keep my fingers crossed. Who knows, maybe by the time the snow gets here, I will be ready and willing for skiing.

Tamara

> Hey Tamara,
> Sorry to hear about the pdoc and stuff. Try to look on the upside though: anafranil (sp?) or clomipramine almost always shows superiority to the SSRI's for a multitude of reasons, one of which, like Paul said, is to increase dopamine outflow by blocking the 2a receptor of serotonin. Another thing going for anafranil is that it has clinically meaningful inhibition of the norepinephrine uptake pump, so to a lesser degree it acts like an NRI.
>
> From my experience, Lexapro and Celexa are worthless, and if I was you, I'd fully substitue the Anafranil for the lex. Other than that, I know you'll be feeling better soon, so keep your chin up. Oh, and of course let us know how the anafranil works out.
>
> Best wishes,
> Justin


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