Posted by jboud24 on November 4, 2004, at 10:03:43
In reply to Saw pdoc - didn't go as I had hoped - scared, posted by jujube on November 3, 2004, at 10:25:56
Sorry to hear about the pdoc and stuff. Try to look on the upside though: anafranil (sp?) or clomipramine almost always shows superiority to the SSRI's for a multitude of reasons, one of which, like Paul said, is to increase dopamine outflow by blocking the 2a receptor of serotonin. Another thing going for anafranil is that it has clinically meaningful inhibition of the norepinephrine uptake pump, so to a lesser degree it acts like an NRI.
From my experience, Lexapro and Celexa are worthless, and if I was you, I'd fully substitue the Anafranil for the lex. Other than that, I know you'll be feeling better soon, so keep your chin up. Oh, and of course let us know how the anafranil works out.