Posted by yznhymer on September 15, 2004, at 4:02:09
In reply to Re: Cymbalta (duloxetine) - report » yznhymer, posted by iris2 on September 14, 2004, at 22:37:05
> Just a thought. With good response to Nardil, have you ever tried Parnate or Marplan? I had a good response to them and not Nardil with slight response to Moclobimide. Someone on this sight mentioned that chemically Cymbalta was close to Parnate. Do not know if it is true or if it is of any significance.
>
> I've had about three decades of atypical depression myself and tried a variety of meds with about the same results as you. As an adjunct to Parnate or Moclobimide I was on reboxetine and ritalin. I tried Selegaline with no patch. No go!
>
> Maybe this will help a little.
>
> ireneThanks Irene. I appreciate the input. Never have tried Parnate or Marplan. I believe my doc's thinking was that the odds of the side effects being similar to Nardil were pretty great. I'd have to agree that if the potential for sexual dysfunction is possible, I'm likely to get hit with it. From what I've read, Selegeline might be a little more forgiving in this department, as well as have some efficacy with the types of symptoms I experience, that is, if it works at all. Likewise, I've read that Cymbalta may not be so harsh in terms of sexual dysfuction as a side effect and may offer greater efficacy than a pure SSRI. In both cases there's only one way to find out, right?
Neither of the pdoc's I've had were willing (able?)to augment moclobemide. Roche Canada refused to give my current pdoc any info when he called (I'm in the states). I did augment moclobemide with DHEA for awhile while involved in a rigorous exercise program... the DHEA and exercise made a BIG difference. Since I've moved, dropped the personal trainer and slid into this slump, I've not been able to muster the motivation and stamina to get a good exercise program going again, though its still a goal! Hmmm... maybe I should restart the DHEA in any event.
Best wishes, Irene, and other posters...
Mark
poster:yznhymer
thread:380308
URL: http://www.dr-bob.org/babble/20040915/msgs/390968.html