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Re: Trouble sleeping - please help

Posted by King Vultan on September 11, 2004, at 21:08:33

In reply to Re: Trouble sleeping - please help » King Vultan, posted by KaraS on September 11, 2004, at 15:47:51

>
> So how have you prevented tolerance to Halcion? Are you only taking it once or twice a week?
>

No, I take it every other night, alternating with either the Benadryl or Unisom.


> Can you tell me more about hydroxyzine and it's use for sleep?
>
>

It's a drug I had never heard of that my pdoc happened to mention on a recent visit. It appears to be a very anxiolytic antihistamine that is mainly used as a sedative. Apparently, it can also be used for sleep, too, and has antinausea properties. My book "Psychotropic Drugs" does not recommend it for routine use as a sedative, but they do recommend chloral hydrate, which strikes me as a little bit strange. I was actually thinking about inquiring about chloral hydrate myself, but it has been shown to cause cancer in mice. I don't know how much chloral hydrate was necessary to give the mice cancer, though, or the implications as far as people.


> Does the fact that I respond paradoxically to dopaminergics mean that I also have presynaptic hypersensitive dopamine autoreceptors or are there other possible explanations? (BTW, Provigil didn't make me sleepy or alert - just produced that leaden limbs feeling. I may not have tried enough to get more of a reaction though.)
>
>

It's quite possible this could be your problem, but it is only a theory, and there might be some other conceivable explanation.


> I should try the Unisom because it would be a cheap and easy fix but I'm so afraid to. The Benadryl was so awful. I was so exhausted and drugged feeling yet my heart was racing (as I said earlier). It's a horrible state to be in because you can't sleep yet you can't do anything else because you're so drugged feeling. Each minute was like an hour. Wish I could know the result without having to do the experiment.
>
> Kara
>

I remained kind of hung over from the two Unisom pills into the afternoon. I think I will go back to one pill next time. It does have a very similar structure to that of Benadryl, but so do the tricyclic antidepressants closely resemble each other also, and they can have very different properties.

Todd


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poster:King Vultan thread:388936
URL: http://www.dr-bob.org/babble/20040909/msgs/389864.html